R45 Beauty The Reversal Skin Transform Retinol Booster 6 Mth Supply NEW Read. Beauty Bio R45 RETINOL BOOSTER - So Powerful you only need the 3 Phase set twice a year. Cleanse face & pat dry. Apply 1-2 pumps of R45 The Reversal Phase 1 Regeneration Complex (Side A) + GFS Serum (Side B) to face. After R$% The Reversal Phase 1 is complete, advance to Phase 2 and conclude with Phase 3. Results are cumulative, don't start with Phase 2 or Phase 3. Follow with your favorite moisturizer. For PM use. Phase 2 is 50% stronger than Phase 1 and Phase 3 is 50% stronger than Phase 2 so it is important to use them in order. These are brand new